Salternamide E from a Saltern-derived Marine Actinomycete Streptomyces sp

نویسندگان

  • Seong-Hwan Kim
  • Yoonho Shin
  • Sang Kook Lee
  • Jongheon Shin
  • Dong-Chan Oh
چکیده

− Comprehensive chemical analysis of extracts and fractions of marine actinomycete strains led to the discovery of a new minor secondary metabolite, salternamide E (1), from a saltern-derived halophilic Streptomyces strain. The planar structure of salternamide E (1) was elucidated by a combinational analysis of spectroscopic data including NMR, MS, UV, and IR. The absolute configuration of salternamide E (1) was determined by circular dichroism spectroscopic analysis. Salternamide E displayed weak cytotoxicity against various human carcinoma cell lines.

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تاریخ انتشار 2016